Glomerular Na+-K+-ATPase activity in acute and chronic diabetes and with aldose reductase inhibition.

@article{Cohen1988GlomerularNA,
  title={Glomerular Na+-K+-ATPase activity in acute and chronic diabetes and with aldose reductase inhibition.},
  author={Margo Panush Cohen and H Klepser},
  journal={Diabetes},
  year={1988},
  volume={37 5},
  pages={558-62}
}
Sorbitol accumulation, myo-inositol depletion, and reduced Na+-K+-ATPase activity have been identified in experimental diabetes in several tissues in which diabetic complications occur. However, a reduction in renal Na+-K+-ATPase activity has not been universally reported, prompting us to examine the influence of diabetes duration on the activity of this… CONTINUE READING