Globulixanthones C, D and E: three prenylated xanthones with antimicrobial properties from the root bark of Symphonia globulifera.

  title={Globulixanthones C, D and E: three prenylated xanthones with antimicrobial properties from the root bark of Symphonia globulifera.},
  author={A. E. Nkengfack and P. Mkounga and M. Meyer and Z. Fomum and B. Bodo},
  volume={61 2},
Two prenylated xanthone derivatives, named globulixanthones C and D and one bis-xanthone, designated globulixanthone E, have been isolated from the root bark of Symphonia globulifera. The structures of these compounds were elucidated by a detailed spectroscopic analysis. They have been shown to exhibit in vitro significant antimicrobial activity against a range of micro-organisms. 
A prenylated xanthone with antimicrobial activity from the seeds of Symphonia Globulifera
A prenylated xanthone has been isolated from the seeds of Symphonia globulifera together with the known compounds sitosterol and oleanolic acid. The structure of the new compound was elucidated byExpand
Globulixanthone F, a New Polyoxygenated Xanthone with an Isoprenoid Group and Two Antimicrobial Biflavonoids from the Stem Bark of Symphonia Globulifera¶
The spectral data of ugaxanthone and mbarraxanthone are reported here for the first time, as well as the antimicrobial activity of globulixanthone F against a range of microorganisms. Expand
Two Unusual Xanthones from the Bark of Garcinia xanthochymus
A new xanthone derivative, garcinexanthone F (1), which was found to possess an α,β-unsaturated γ-lactone moiety, and a new bisxanthone, bigarcinenone B (2), with a terpene bridge providing theExpand
Afzeliixanthones A and B, two new prenylated xanthones from Garcinia afzelii ENGL. (Guttiferae).
Two new prenylated xanthones, afzeliixanthones A and B, were isolated from the CH2Cl2/MeOH (1:1) extract of the stem bark of Garcinia afzelii ENGL, collected in the South West Province of Cameroon. Expand
Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).
A LC/ESI-MS(n) study performed on polyprenylated benzophenones previously isolated from Moronobea coccinea provided a reliable method for their detection in the extract and structural elucidation. Expand
Symphonia globulifera, a widespread source of complex metabolites with potent biological activities.
The natural occurrence, botanical aspects, ethnomedicinal use, structure, and biogenesis, as well as biological activities of compounds isolated from this species according to their provenance are described. Expand
Chemical constituents of garcinia prainiana
Five compounds identified as friedelin 1, eupha-8, 24- diene 3-β-ol 2, stigmasterol 3, teraxerone 4 and teraxerol 5 have been isolated from Garcinia prainiana (Guttiferae) for the first time. ThereExpand
Paeciloxanthone, a new cytotoxic xanthone from the marine mangrove fungus Paecilomyces sp. (Tree1-7)
The metatrophic fungus Paecilomyces sp. (Tree1-7) was isolated from an estuarine mangrove from the Taiwan Strait. The methanol extract of the fungal mycelium exhibited cytotoxicity against hepG2.Expand
Xanthones from the stems of Cudrania tricuspidata and their inhibitory effects on pancreatic lipase and fat accumulation.
Xanthones from the stems of C. tricuspidata exerted pancreatic lipase inhibitory activity and reduced the fat accumulation in liver cells stimulated with fatty acids, suggesting that these compounds might be beneficial in the treatment of metabolic diseases. Expand
11 - Xanthones and Anthranoids from the Medicinal Plants of Africa
This chapter summarizes the occurrence of these two classes of compounds in African plants, together with their biological/pharmacological activities, and examines the biosynthetic pathways of xanthones and anthrones (or anthronoids). Expand


Globulixanthones A and B, two new cytotoxic xanthones with isoprenoid groups from the root bark of Symphonia globulifera.
Bioassay-guided fractionation of a root bark extract of Symphonia globulifera has yielded two new xanthones with isoprenoid units, named globulixanthones A and B, which possess significant cytotoxicity in vitro against the KB cell line. Expand
Two xanthones from root bark of Calophyllum inophyllum
Two new xanthones, named caloxanthones A and B, were isolated from the root bark of Calophyllum inophyllum, in addition to known xanthones (macluraxanthone and 1,5-dihydroxyxanthone) andExpand
Novel metabolites from ploiarium alternifolium: A bixanthone and two anthraquinonylxanthones
From branches of the shrub Plotarium atternifolium three novel metabolites have been isolated: a CC'—linked bixanthone, ploiarixanthone(1). and two anthraquinonylxanthones, euxanmodin A and B (2 andExpand
Tetraoxygenated naturally occurring xanthones.
This review, with 350 references, gives information on the chemical study of 234 naturally occurring tetraoxygenated xanthones in 12 families, 53 genus and 182 species of higher plants, and two whichExpand
Dulxanthones F-H, three new pyranoxanthones from Garcinia dulcis.
Three new pyranoxanthones, dulxanthones F-H (1-3), have been isolated from the leaves of Garcinia dulcis on the basis of extensive NMR studies. Expand
Structure of chiratanin, a novel dimeric xanthone
A novel dimeric xanthone, chiratanin has been isolated from Swertia chirata Buch. Ham. Gentianaceae). The structure of the compound was elucidated from spectral studies.
Carbon-13 NMR of flavonoids
1. Introduction (P.K. Agrawal, K.R. Markham). Flavonoid structure variation - nomenclature. Flavonoid structure establishment - general. Revision of flavonoid structures resulting from carbon-13 NMRExpand