Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells.

@article{Corti2016GlobinXI,
  title={Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells.},
  author={Paola Corti and Jianmin Xue and Jes{\'u}s Tejero and Nadeem Wajih and Ming Sun and Donna B Stolz and Michael Tsang and Daniel B. Kim-Shapiro and Mark T Gladwin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2016},
  volume={113 30},
  pages={8538-43}
}
The discovery of novel globins in diverse organisms has stimulated intense interest in their evolved function, beyond oxygen binding. Globin X (GbX) is a protein found in fish, amphibians, and reptiles that diverged from a common ancestor of mammalian hemoglobins and myoglobins. Like mammalian neuroglobin, GbX was first designated as a neuronal globin in fish and exhibits six-coordinate heme geometry, suggesting a role in intracellular electron transfer reactions rather than oxygen binding… CONTINUE READING
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