Globally, unrelated protein sequences appear random

  title={Globally, unrelated protein sequences appear random},
  author={Daniel T. Lavelle and William R. Pearson},
  volume={26 3},
MOTIVATION To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared the frequencies of four- and five-amino acid word clumps (independent words) in proteins to the frequencies predicted by four random sequence models. RESULTS While the human… CONTINUE READING