Global transcriptional responses of fission yeast to environmental stress.

@article{Chen2003GlobalTR,
  title={Global transcriptional responses of fission yeast to environmental stress.},
  author={Dongrong Chen and William Toone and Juan Mata and Rachel Lyne and Gavin James Burns and Katja Kivinen and Alvis Brazma and Nicholas Jones and J{\"u}rg B{\"a}hler},
  journal={Molecular biology of the cell},
  year={2003},
  volume={14 1},
  pages={
          214-29
        }
}
We explored transcriptional responses of the fission yeast Schizosaccharomyces pombe to various environmental stresses. DNA microarrays were used to characterize changes in expression profiles of all known and predicted genes in response to five stress conditions: oxidative stress caused by hydrogen peroxide, heavy metal stress caused by cadmium, heat shock caused by temperature increase to 39 degrees C, osmotic stress caused by sorbitol, and DNA damage caused by the alkylating agent… CONTINUE READING

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