Global repositioning of transcription start sites in a plant-fermenting bacterium

@inproceedings{Boutard2016GlobalRO,
  title={Global repositioning of transcription start sites in a plant-fermenting bacterium},
  author={Magali Boutard and Laurence M Ettwiller and Tristan Cerisy and Adriana Alberti and Karine Labadie and Marcel Salanoubat and Ira Schildkraut and Andrew C Tolonen},
  booktitle={Nature communications},
  year={2016}
}
  • Magali Boutard, Laurence M Ettwiller, +5 authors Andrew C Tolonen
  • Published in Nature communications 2016
  • Medicine, Biology
  • Bacteria respond to their environment by regulating mRNA synthesis, often by altering the genomic sites at which RNA polymerase initiates transcription. Here, we investigate genome-wide changes in transcription start site (TSS) usage by Clostridium phytofermentans, a model bacterium for fermentation of lignocellulosic biomass. We quantify expression of nearly 10,000 TSS at single base resolution by Capp-Switch sequencing, which combines capture of synthetically capped 5' mRNA fragments with… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    7
    Twitter Mentions

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 10 CITATIONS

    Capping-RACE: a simple, accurate, and sensitive 5′ RACE method for use in prokaryotes

    VIEW 9 EXCERPTS
    CITES METHODS
    HIGHLY INFLUENCED

    Bacterial RNA Biology on a Genome Scale.

    VIEW 1 EXCERPT
    CITES METHODS

    Evolution of a Biomass-Fermenting Bacterium To Resist Lignin Phenolics.

    VIEW 1 EXCERPT
    CITES BACKGROUND