Global remodeling of nucleosome positions in C. elegans

  title={Global remodeling of nucleosome positions in C. elegans},
  author={George Locke and Devorah M Haberman and Steven M. Johnson and Alexandre V. Morozov},
  booktitle={BMC Genomics},
Eukaryotic chromatin architecture is affected by intrinsic histone-DNA sequence preferences, steric exclusion between nucleosome particles, formation of higher-order structures, and in vivo activity of chromatin remodeling enzymes. To disentangle sequence-dependent nucleosome positioning from the other factors, we have created two high-throughput maps of nucleosomes assembled in vitro on genomic DNA from the nematode worm Caenorhabditis elegans. A comparison of in vitro nucleosome positions… CONTINUE READING
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