Global regulation of gene expression by ArlRS, a two-component signal transduction regulatory system of Staphylococcus aureus.

@article{Liang2005GlobalRO,
  title={Global regulation of gene expression by ArlRS, a two-component signal transduction regulatory system of Staphylococcus aureus.},
  author={Xudong Liang and Li Zheng and Christina Landwehr and Dwayne Lunsford and David Holmes and Yinduo Ji},
  journal={Journal of bacteriology},
  year={2005},
  volume={187 15},
  pages={5486-92}
}
Staphylococcus aureus expresses various cell wall-associated and extracellular virulence factors, coordinately controlled by different two-component signal transduction systems and transcriptional regulators. In this study, we used microarray technology to identify the genes regulated by ArlR. The microarray data indicate that ArlR functions as a positive regulator and also as a negative repressor to directly and/or indirectly mediate the expression of at least 114 genes involved in different… CONTINUE READING

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