Global proteomic profiling in multistep hepatocarcinogenesis and identification of PARP1 as a novel molecular marker in hepatocellular carcinoma

@inproceedings{Xu2016GlobalPP,
  title={Global proteomic profiling in multistep hepatocarcinogenesis and identification of PARP1 as a novel molecular marker in hepatocellular carcinoma},
  author={Xiao Xu and Zhikun Liu and Jianguo Wang and Hai-Yang Xie and Jie Li and Jili Cao and Lin Zhou and Shusen Zheng},
  booktitle={Oncotarget},
  year={2016}
}
The more accurate biomarkers have long been desired for hepatocellular carcinoma (HCC). Here, we characterized global large-scale proteomics of multistep hepatocarcinogenesis in an attempt to identify novel biomarkers for HCC. Quantitative data of 37874 sequences and 3017 proteins during hepatocarcinogenesis were obtained in cohort 1 of 75 samples (5 pooled… CONTINUE READING