Global proteome analysis of hepatitis B virus expressing human hepatoblastoma cell line HepG2.

Abstract

In countries where hepatitis B virus (HBV) is endemic, a high incidence of hepatocellular carcinoma (HCC) occur in HBV carriers and the prolonged replication and expression of HBV proteins in the liver is considered an important risk factor for progression to malignancy. However, the mechanism of pathogenesis of HBV-associated carcinoma remains elusive. In… (More)
DOI: 10.1002/jmv.21593

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