Global modeling of transcriptional responses in interaction networks

@article{Lahti2010GlobalMO,
  title={Global modeling of transcriptional responses in interaction networks},
  author={Leo Lahti and Juha E. A. Knuuttila and Samuel Kaski},
  journal={Bioinformatics},
  year={2010},
  volume={26 21},
  pages={
          2713-20
        }
}
MOTIVATION Cell-biological processes are regulated through a complex network of interactions between genes and their products. The processes, their activating conditions and the associated transcriptional responses are often unknown. Organism-wide modeling of network activation can reveal unique and shared mechanisms between tissues, and potentially as yet unknown processes. The same method can also be applied to cell-biological conditions in one or more tissues. RESULTS We introduce a novel… 

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