Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer

Abstract

The EGFR-driven cell-cycle pathway has been extensively studied due to its pivotal role in breast cancer proliferation and pathogenesis. Although several studies reported regulation of individual pathway components by microRNAs (miRNAs), little is known about how miRNAs coordinate the EGFR protein network on a global miRNA (miRNome) level. Here, we combined… (More)
DOI: 10.1038/msb.2011.100

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