Global fibrinolytic capacity is decreased in polycystic ovary syndrome, suggesting a prothrombotic state.

@article{Yildiz2002GlobalFC,
  title={Global fibrinolytic capacity is decreased in polycystic ovary syndrome, suggesting a prothrombotic state.},
  author={B{\"u}lent Okan Yildiz and Ibrahim Celalettin Haznedaroğlu and Serafettin Kirazli and M. D.. Miyase Bayraktar},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2002},
  volume={87 8},
  pages={3871-5}
}
The polycystic ovary syndrome (PCOS) is associated with an increased risk of cardiovascular disease (CVD). Insulin resistance (IR), hyperandrogenism, and dyslipidemia are well-known cardiovascular risk factors in PCOS. Impaired fibrinolysis could also contribute to the development of CVD in PCOS. Global fibrinolytic capacity (GFC) is a recently developed method, which is reflected by the amount of generated D-dimer when the fibrinolysis of a freeze-dried fibrin clot is stopped by introducing… CONTINUE READING

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