Global expression profiles from C57BL/6J and DBA/2J mouse lungs to determine aging-related genes.


This study identified gene expression profiles that provided evidence for genomic mechanisms underlying the pathophysiology of aging lung. Aging lungs from C57BL/6 (B6) and DBA/2 (D2) mouse strains differ in physiology and morphometry. Lungs were harvested from B6 mice at 2, 18, and 26 mo and from D2 mice at 2 and 18 mo of age. Purified RNA was subjected to… (More)

10 Figures and Tables


  • Presentations referencing similar topics