Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays.

@article{Maitra2003GlobalEA,
  title={Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays.},
  author={Anirban Maitra and Donna E Hansel and Pedram Argani and Raheela Ashfaq and Ayman A. Rahim A. Rahman and Ali Naji and Shaoping Deng and Joseph Geradts and Lesleyann Hawthorne and Michael G. House and Charles J Yeo},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2003},
  volume={9 16 Pt 1},
  pages={5988-95}
}
PURPOSE Pancreatic endocrine neoplasms (PENs) are rare, mostly well-differentiated endocrine neoplasms, whose biology has been poorly characterized. Global expression microarrays can document abnormal pathways that impact on tumorigenesis and disease progression. EXPERIMENTAL DESIGN RNA was extracted from eight well-differentiated PENs and three highly enriched pancreatic islet cell samples (80-90% purity), and examined using the Affymetrix U133A oligonucleotide microarray. Microarray data… CONTINUE READING

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