Global dissemination of a multidrug resistant Escherichia coli clone.

  title={Global dissemination of a multidrug resistant Escherichia coli clone.},
  author={Nicola K. Petty and Nouri L Ben Zakour and Mitchell Stanton-Cook and Elizabeth Skippington and Makrina Totsika and Brian M Forde and Minh-Duy Phan and Danilo Gomes Moriel and Kate Peters and Mark Davies and Benjamin A Rogers and G. Dougan and Jes{\'u}s Rodr{\'i}guez-Ba{\~n}o and {\'A}lvaro Pascual and Johann D D Pitout and Mathew Upton and David L Paterson and Timothy R. Walsh and Mark A Schembri and Scott A. Beatson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={111 15},
Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR) clone responsible for a high proportion of urinary tract and bloodstream infections. The rapid emergence and successful spread of E. coli ST131 is strongly associated with several factors, including resistance to fluoroquinolones, high virulence gene content, the possession of the type 1 fimbriae FimH30 allele, and the production of the CTX-M-15 extended spectrum β-lactamase (ESBL). Here, we used… CONTINUE READING
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