Global control of hepatitis B virus infection.

@article{Kao2002GlobalCO,
  title={Global control of hepatitis B virus infection.},
  author={Jia-Horng Kao and Ding-Shinn Chen},
  journal={The Lancet. Infectious diseases},
  year={2002},
  volume={2 7},
  pages={
          395-403
        }
}
Worldwide about 350 million people are chronic carriers of the hepatitis B virus (HBV). The infection can cause acute and chronic liver disease including cirrhosis and hepatocellular carcinoma (HCC). Hepatocellular injuries of HBV infection are predominantly immune-mediated, and the natural history of chronic infection can be divided into three phases based on virus-host interactions-namely, immune tolerance, immune clearance, and viral integration phases. Four serotypes (adw, ayw, adr, and ayr… CONTINUE READING

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