Global clinical trials for the treatment of TB with thioridazine.

  • Martin J. Boeree
  • Published 2011 in Recent patents on anti-infective drug discovery


Current evidence shows that thioridazine (THZ) is ready for global clinical evaluation, while some of its derivatives and other efflux pump inhibitors reach the end stage of preclinical evaluation. In this paper, a clinical trial plan is described that investigates the antituberculosis potency, the safety profile and the role of THZ and/or its derivatives… (More)


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