Global cardiac-specific transgene expression using cardiopulmonary bypass with cardiac isolation.

Abstract

BACKGROUND The available techniques for intravascular gene delivery to the heart are inefficient and not organ-specific. Yet, effective treatment of heart failure will likely require transgene expression by the majority of cardiac myocytes. To address this problem, we developed a novel cannulation technique that achieves efficient isolation of the heart in… (More)

Topics

  • Presentations referencing similar topics