Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study

@article{ODonnell2016GlobalAR,
  title={Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study},
  author={Martin O’Donnell and Siu Lim Chin and Sumathy Rangarajan and Denis Xavier and Li-sheng Liu and Hong-ye Zhang and Purnima Rao-Melacini and Xiaohe Zhang and Prem Pais and Steven Agapay and Patricio L{\'o}pez-Jaramillo and Albertino Damasceno and Peter Langhorne and Matthew J. McQueen and Annika Rosengren and Mahshid Dehghan and Graeme J. Hankey and Antonio Miguel L. Dans and Ahmed Elsayed and Alvaro Avezum and Charles Kiiza Mondo and Hans Christoph Diener and Danuta Ryglewicz and Anna Członkowska and N. V. Pogosova and Christian Weimar and Romaina Iqbal and Rafael Diaz and Khalid Yusoff and Afzal Hussein Yusufali and Aytekin Oguz and Xingyu Wang and Ernesto Pe{\~n}aherrera and Fernando Lanas and Okechukwu Samuel Ogah and Adesola Ogunniyi and Helle Klingenberg Iversen and Germ{\'a}n M{\'a}laga and Zvonko Rumboldt and Shahram Oveisgharan and Fawaz Al Hussain and Daliwonga Magazi and Yongchai Nilanont and John Ferguson and Guillaume Par{\'e} and Salim Yusuf},
  journal={The Lancet},
  year={2016},
  volume={388},
  pages={761-775}
}
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1,036 Citations
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References

SHOWING 1-10 OF 60 REFERENCES
Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study
Rationale and Design of INTERSTROKE: A Global Case-Control Study of Risk Factors for Stroke
TLDR
An effective global strategy to reduce the risk of stroke mandates systematic measurement of the contribution of the major vascular risk factors within defined ethnic groups and geographical locations.
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
New strategy to reduce the global burden of stroke.
TLDR
The increasing burden of stroke and other major NCDs provide strong support for the notion that the currently used primary prevention strategies for stroke andOther major N CDs (business as usual) are not sufficiently effective.
Age- and Sex-Specific Burden of Cardiovascular Disease Attributable to 5 Major and Modifiable Risk Factors in 10 Asian Countries of the Western Pacific Region.
TLDR
This review derives the most reliable and previously unpublished estimates of the age- and sex-specific burden of vascular disease attributable to the aforementioned risk factors for 10 of the most populous Asian countries in the Western Pacific Region.
Association of atrial fibrillation with mortality and disability after ischemic stroke
TLDR
Older age and increased stroke severity explain most of the association between AF and poorer outcomes after acute ischemic stroke, and nonuse of oral anticoagulant therapy represents the most important modifiable care gap to mitigate the association.
Ethnic Differences in Risk Factors for Ischemic Stroke: A European Case–Control Study
TLDR
In the first European case-control study examining risk factors for ischemic stroke in black Caribbean and African populations, some differences were demonstrated in the impact of risk factors between these groups.
A Comparative Analysis of Risk Factors and Stroke Risk for Asian and Non-Asian Men: The Asia Pacific Cohort Studies Collaboration
  • K. Hyun, R. Huxley, M. Woodward
  • Medicine, Psychology
    International journal of stroke : official journal of the International Stroke Society
  • 2013
Background The risk of stroke is high in men among both Asian and non-Asian populations, despite differences in risk factor profiles; whether risk factors act similarly in these populations is…
Cardiovascular risk and events in 17 low-, middle-, and high-income countries.
TLDR
Although the risk-factor burden was lowest in low-income countries, the rates of major cardiovascular disease and death were substantially higher inLow- Income countries than in high- income countries, which may have been mitigated by better control of risk factors.
...
...