Global analysis of gene-level microRNA expression in Arabidopsis using deep sequencing data.

@article{Yang2011GlobalAO,
  title={Global analysis of gene-level microRNA expression in Arabidopsis using deep sequencing data.},
  author={Xiaozeng Yang and Huiyong Zhang and Lei Li},
  journal={Genomics},
  year={2011},
  volume={98 1},
  pages={40-6}
}
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level in eukaryotes. Exclusive focus on mature miRNA in most expression profiling efforts has prevented effective measurement of the expression of individual miRNA (MIR) genes. Using three sequenced small RNA libraries, we adapted miRDeep, which employs a probabilistic model of miRNA biogenesis, to analyze the miRNA transcriptome in Arabidopsis. We determined that less than 40% annotated MIR genes are expressed in shoot… CONTINUE READING
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