Global analysis of altered gene expression during morphogenesis of Candida albicans in vitro.

@article{Singh2005GlobalAO,
  title={Global analysis of altered gene expression during morphogenesis of Candida albicans in vitro.},
  author={Vijender Singh and Indranil Sinha and P. P. Sadhale},
  journal={Biochemical and biophysical research communications},
  year={2005},
  volume={334 4},
  pages={1149-58}
}
Candida albicans, a commensal of the gastrointestinal and uro vaginal tract can cause life-threatening infections under conditions of lowered immunity of the host. The changes in the host environment that are sensed by the pathogen which elicit this response have not yet been clearly identified. We report here that co-incubation with a macrophage cell line in vitro for extended period of time (16 h) leads to lysis of the macrophage cells. The altered condition in growth medium induces… CONTINUE READING