Global adaptations resulting from high population densities in Escherichia coli cultures.

@article{Liu2000GlobalAR,
  title={Global adaptations resulting from high population densities in Escherichia coli cultures.},
  author={Xiang Liu and Ching Ching Ng and Thomas Ferenci},
  journal={Journal of bacteriology},
  year={2000},
  volume={182 15},
  pages={4158-64}
}
The scope of population density effects was investigated in steady-state continuous cultures of Escherichia coli in the absence of complications caused by transient environmental conditions and growth rates. Four distinct bacterial properties reflecting major regulatory and physiological circuits were analyzed. The metabolome profile of bacteria growing at high density contained major differences from low-density cultures. The 10-fold-elevated level of trehalose at higher densities pointed to… CONTINUE READING

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