Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins

@article{Tishkoff1996GlobalPO,
  title={Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins},
  author={S. Tishkoff and E. Dietzsch and W. Speed and A. Pakstis and J. Kidd and K. Cheung and B. Bonn{\'e}-Tamir and A. Santachiara‐Benerecetti and P. Moral and M. Krings and S. P{\"a}{\"a}bo and E. Watson and N. Risch and T. Jenkins and K. Kidd},
  journal={Science},
  year={1996},
  volume={271},
  pages={1380 - 1387}
}
  • S. Tishkoff, E. Dietzsch, +12 authors K. Kidd
  • Published 1996
  • Biology, Medicine
  • Science
  • Key MethodHaplotypes consisting of alleles at a short tandem repeat polymorphism (STRP) and an Alu deletion polymorphism at the CD4 locus on chromosome 12 were analyzed in more than 1600 individuals sampled from 42 geographically dispersed populations (13 African, 2 Middle Eastern, 7 European, 9 Asian, 3 Pacific, and 8 Amerindian). Sub-Saharan African populations had more haplotypes and exhibited more variability in frequencies of haplotypes than the Northeast African or non-African populations. The Alu…Expand Abstract
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