Global Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii

@inproceedings{Zhou2015GlobalMP,
  title={Global Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii},
  author={Chaohua Zhou and Dong-Hui Zhou and Hany M. Elsheikha and Guang-xue Liu and Xuxiang Suo and Xing-Quan Zhu and Laura J Knoll},
  booktitle={PloS one},
  year={2015}
}
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabolomics strategy to identify differentially regulated metabolites and affected metabolic pathways in BALB/c mice during infection with T. gondii Pru strain at 7, 14 and 21 days post-infection (DPI… CONTINUE READING

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