Global Mapping of H3K4me1 and H3K4me3 Reveals the Chromatin State-Based Cell Type-Specific Gene Regulation in Human Treg Cells

Abstract

Regulatory T cells (Treg) contribute to the crucial immunological processes of self-tolerance and immune homeostasis. Genomic mechanisms that regulate cell fate decisions leading to Treg or conventional T cells (Tconv) lineages and those underlying Treg function remain to be fully elucidated, especially at the histone modification level. We generated high… (More)
DOI: 10.1371/journal.pone.0027770

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@inproceedings{Tian2011GlobalMO, title={Global Mapping of H3K4me1 and H3K4me3 Reveals the Chromatin State-Based Cell Type-Specific Gene Regulation in Human Treg Cells}, author={Yi Tian and Zhengcai Jia and Jun Wang and Zemin Huang and Jun Tang and Yanhua Zheng and Yan Tang and Qinghong Wang and Zhiqiang Tian and Di Yang and Yi Zhang and Xiaolan Fu and Jianxun Song and Shunli Liu and Jennifer C. van Velkinburgh and Yu-zhang Wu and Bing Ni}, booktitle={PloS one}, year={2011} }