Global DNA methylation and low-level exposure to benzene.


INTRODUCTION Global genomic hypomethylation is a common event in cancer tissues that is frequently observed in hematopoietic malignancies, including leukemia. Benzene, an established leukemogen at high doses, has been suggested to induce hypomethylation based on investigations of DNA methylation in LINE-1 and Alu repetitive elements. Whether global genomic… (More)


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@article{Fustinoni2012GlobalDM, title={Global DNA methylation and low-level exposure to benzene.}, author={Silvia Fustinoni and Federica Rossella and Elisa Polledri and Valentina Bollati and Laura Del Campo and Hyang-Min Byun and Luciano Agnello and Dario Consonni and Angela Cecilia Pesatori and Andrea A. Baccarelli and Pier Alberto Bertazzi}, journal={La Medicina del lavoro}, year={2012}, volume={103 2}, pages={84-95} }