Global Co-Existence of Two Evolutionary Lineages of Parvovirus B19 1a, Different in Genome-Wide Synonymous Positions

@inproceedings{Backer2012GlobalCO,
  title={Global Co-Existence of Two Evolutionary Lineages of Parvovirus B19 1a, Different in Genome-Wide Synonymous Positions},
  author={Marijke W. A. Molenaar-de Backer and Vladimir V. Lukashov and Rob S. van Binnendijk and H. J. G. Boot and Hans L. Zaaijer},
  booktitle={PloS one},
  year={2012}
}
Parvovirus B19 (B19V) can cause infection in humans. To date, three genotypes of B19V, with subtypes, are known, of which genotype 1a is the most prevalent genotype in the Western world. We sequenced the genome of B19V strains of 65 asymptomatic, recently infected Dutch blood donors, to investigate the spatio-temporal distribution of B19V strains, in the years 2003-2009. The sequences were compared to B19V sequences from Dutch patients with fifth disease, and to global B19V sequences as… CONTINUE READING

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