Global Analysis of the Relationship between JIL-1 Kinase and Transcription

@inproceedings{Regnard2011GlobalAO,
  title={Global Analysis of the Relationship between JIL-1 Kinase and Transcription},
  author={Catherine Regnard and Tobias Straub and Angelika Mitterweger and Ina K. Dahlsveen and Viola Fabian and Peter B. Becker},
  booktitle={PLoS genetics},
  year={2011}
}
The ubiquitous tandem kinase JIL-1 is essential for Drosophila development. Its role in defining decondensed domains of larval polytene chromosomes is well established, but its involvement in transcription regulation has remained controversial. For a first comprehensive molecular characterisation of JIL-1, we generated a high-resolution, chromosome-wide interaction profile of the kinase in Drosophila cells and determined its role in transcription. JIL-1 binds active genes along their entire… CONTINUE READING

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