Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase.

Abstract

Gln-tRNA(Gln) is synthesized from Glu-tRNA(Gln) in most microorganisms by a tRNA-dependent amidotransferase in a reaction requiring ATP and an amide donor such as glutamine. GatDE is a heterodimeric amidotransferase that is ubiquitous in Archaea. GatD resembles bacterial asparaginases and is expected to function in amide donor hydrolysis. We show here that… (More)

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Cite this paper

@article{Feng2005GlntRNAGlnFF, title={Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase.}, author={Liang Feng and Kelly - Ann Sheppard and Debra Tumbula-Hansen and Dieter S{\"o}ll}, journal={The Journal of biological chemistry}, year={2005}, volume={280 9}, pages={8150-5} }