Gliotoxin effects on fungal growth: mechanisms and exploitation.

  title={Gliotoxin effects on fungal growth: mechanisms and exploitation.},
  author={Stephen Carberry and Emer L Molloy and Stephen Hammel and Gr{\'a}inne O'Keeffe and Gary W. Jones and Kevin Kavanagh and Sean Doyle},
  journal={Fungal genetics and biology : FG & B},
  volume={49 4},
Although initially investigated for its antifungal properties, little is actually known about the effect of gliotoxin on Aspergillus fumigatus and other fungi. We have observed that exposure of A. fumigatus to exogenous gliotoxin (14 μg/ml), under gliotoxin-limited growth conditions, results in significant alteration of the expression of 27 proteins (up… CONTINUE READING