Glioma epigenetics: From subclassification to novel treatment options.

Abstract

Gliomas are the most common malignant primary brain tumors, of which glioblastoma is the most malignant form (WHO grade IV), and notorious for treatment resistance. Over the last decade mutations in epigenetic regulator genes have been identified as key drivers of subtypes of gliomas with distinct clinical features. Most characteristic are mutations in IDH1… (More)
DOI: 10.1016/j.semcancer.2017.11.010

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Cite this paper

@article{Gusyatiner2017GliomaEF, title={Glioma epigenetics: From subclassification to novel treatment options.}, author={Olga Gusyatiner and Monika E Hegi}, journal={Seminars in cancer biology}, year={2017} }