Glioma cells under hypoxic conditions block the brain microvascular endothelial cell death induced by serum starvation.

@article{Ueda2005GliomaCU,
  title={Glioma cells under hypoxic conditions block the brain microvascular endothelial cell death induced by serum starvation.},
  author={Yoshifumi Ueda and Takao Nakagawa and Toshihiko Kubota and Kazunori Ido and Kazufumi Kawasaki Sato},
  journal={Journal of neurochemistry},
  year={2005},
  volume={95 1},
  pages={
          99-110
        }
}
Angiogenesis is one of essential components for the growth of neoplasms, including malignant gliomas. However, tumor vascularization is often poorly organized and marginally functional due to tumor structural abnormalities, inducing regional or temporal hypoxic conditions and nutritional shortages in tumor tissues. We investigated how during angiogenesis migrating endothelial cells survive in these hypoxic and reduced nutritional conditions. Human brain microvascular endothelial cells (HBMECs… CONTINUE READING
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