Glioblastomas: correlation between oligodendroglial components, genetic abnormalities, and prognosis

Abstract

It has been demonstrated that a small percentage (approximately 15%) of glioblastomas (GBM) presents an oligodendroglial component with a variable frequency of chromosome 1p and 19q deletions, the genetic alteration related to chemotherapy response and longer survival in oligodendrogliomas. There is a growing interest in investigating 1p and 19q losses in… (More)
DOI: 10.1007/s00428-007-0562-9

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