Glioblastoma of pineal region: report of four cases and literature review.


We report four cases of glioblastoma in the pineal region. The patients presented a severe headache and vomiting. Brain imaging showed a heterogeneously enhanced tumor in the pineal region with obstructive hydrocephalus. Case 3 developed a subependymal dissemination. The patient went to ventricular-peritoneal shunt and subtotal or total resection and radiotherapy with/without chemotherapy. Cases 1 and 2 received radiation and died 8 and 11 later months. Cases 3 and 4 completed radiotherapy and chemotherapy, and survived 28 and 31 months after the initial diagnosis. Glioblastoma in the pineal region carry a poor prognosis and require neurooncology teams.

DOI: 10.2217/cns-2016-0047

Cite this paper

@article{Orrego2017GlioblastomaOP, title={Glioblastoma of pineal region: report of four cases and literature review.}, author={Enrique Orrego and Sandro A. A. Casavilca and Pamela Garc{\'i}a-Corrochano and Sugey Rojas-Meza and Miluska Castillo and C A Castaneda}, journal={CNS oncology}, year={2017} }