Glial scar and neuroregeneration: histological, functional, and magnetic resonance imaging analysis in chronic spinal cord injury.

  title={Glial scar and neuroregeneration: histological, functional, and magnetic resonance imaging analysis in chronic spinal cord injury.},
  author={Rong Hu and Jian-jun Zhou and Chunxia Luo and Jiangkai Lin and Xian-rong Wang and Xiaoguang Li and Xiu-wu Bian and YunQing Li and Qi Wan and Yanbing Yu and Hua Feng},
  journal={Journal of neurosurgery. Spine},
  volume={13 2},
OBJECT A glial scar is thought to be responsible for halting neuroregeneration following spinal cord injury (SCI). However, little quantitative evidence has been provided to show the relationship of a glial scar and axonal regrowth after injury. METHODS In this study performed in rats and dogs, a traumatic SCI model was made using a weight-drop injury device, and tissue sections were stained with H & E for immunohistochemical analysis. The function and behavior of model animals were tested… 

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