Glial fibrillary acidic protein is reduced in cerebellum of subjects with major depression, but not schizophrenia

@article{Fatemi2004GlialFA,
  title={Glial fibrillary acidic protein is reduced in cerebellum of subjects with major depression, but not schizophrenia},
  author={S Hossein Fatemi and Jessica Ann Laurence and Mohsen Araghi-Niknam and Joel M. Stary and Irving I Gottesman},
  journal={Schizophrenia Research},
  year={2004},
  volume={69},
  pages={317-323}
}
Glial fibrillary acidic protein (GFAP) is a major protein of astrocyte intermediate filaments and a specific marker for astrocytes. Alterations in levels of GFAP may reflect pathological regulation of neuronal function and survival as well as abnormal synaptogenesis and neurotransmission. We employed quantitative gel electrophoresis and Western blotting to measure levels of GFAP in cerebella of 60 subjects divided equally among schizophrenia, bipolar disorder, major depression, and normal… CONTINUE READING
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