Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury.

@article{Laranjeira2011GlialCI,
  title={Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury.},
  author={C{\'a}tia Laranjeira and Katarina Sandgren and Nicoletta Kessaris and William Richardson and Alexandre J Potocnik and Pieter Vanden Berghe and Vassilis Pachnis},
  journal={The Journal of clinical investigation},
  year={2011},
  volume={121 9},
  pages={
          3412-24
        }
}
  • Cátia Laranjeira, Katarina Sandgren, +4 authors Vassilis Pachnis
  • Published 2011
  • Biology, Medicine
  • The Journal of clinical investigation
  • The enteric nervous system (ENS) in mammals forms from neural crest cells during embryogenesis and early postnatal life. Nevertheless, multipotent progenitors of the ENS can be identified in the adult intestine using clonal cultures and in vivo transplantation assays. The identity of these neurogenic precursors in the adult gut and their relationship to the embryonic progenitors of the ENS are currently unknown. Using genetic fate mapping, we here demonstrate that mouse neural crest cells… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 210 CITATIONS, ESTIMATED 54% COVERAGE

    Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut.

    VIEW 14 EXCERPTS
    CITES BACKGROUND & RESULTS
    HIGHLY INFLUENCED

    Nestin-expressing cells in the gut give rise to enteric neurons and glial cells.

    VIEW 1 EXCERPT
    CITES RESULTS

    FILTER CITATIONS BY YEAR

    2011
    2020

    CITATION STATISTICS

    • 14 Highly Influenced Citations

    • Averaged 19 Citations per year from 2018 through 2020

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 58 REFERENCES

    Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine.

    VIEW 12 EXCERPTS
    HIGHLY INFLUENTIAL