Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury.

Abstract

The enteric nervous system (ENS) in mammals forms from neural crest cells during embryogenesis and early postnatal life. Nevertheless, multipotent progenitors of the ENS can be identified in the adult intestine using clonal cultures and in vivo transplantation assays. The identity of these neurogenic precursors in the adult gut and their relationship to the… (More)
DOI: 10.1172/JCI58200

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