Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia.

@article{Borlongan2000GlialCS,
  title={Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia.},
  author={Cesario V. Borlongan and Masayuki Yamamoto and Norio Takei and Masafumi Kumazaki and C Ungsuparkorn and Hideki Hida and Paul R. Sanberg and Hitoo Nishino},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2000},
  volume={14 10},
  pages={1307-17}
}
The role of glial cells in neuronal death has become a major research interest. Glial cell activation has been demonstrated to accompany cerebral ischemia. However, there is disagreement whether such gliosis is a cell death or a neuroprotective response. In the present study, we examined alterations in glial cell responses to the reported neuroprotective action of the free radical scavenger, melatonin, against cerebral ischemia. Adult male Wistar rats were given oral injections of either… CONTINUE READING
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