Glial cell-mediated deterioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography.

@article{Yu2010GlialCD,
  title={Glial cell-mediated deterioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography.},
  author={Iwae Yu and Motoki Inaji and J. S. Maeda and Takashi Okauchi and T Nariai and Kikuo Ohno and Makoto Higuchi and Tetsuya Suhara},
  journal={Journal of neurotrauma},
  year={2010},
  volume={27 8},
  pages={
          1463-75
        }
}
Traumatic brain injury (TBI) is one of the most acute degenerative pathologies in the central nervous system, and in vivo indices enabling an assessment of TBI on a mechanistic basis have yet to be established. The aim of this work was to pursue neuroinflammatory changes and their link to functional disruptions of traumatically-damaged neurons in a rat model of TBI by longitudinal positron emission tomographic (PET) assays. TBI was induced in the unilateral frontal cortex of craniotomied rats… CONTINUE READING
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