Glial cell influence on the human blood-brain barrier.

@article{Prat2001GlialCI,
  title={Glial cell influence on the human blood-brain barrier.},
  author={Alexandre Prat and Katherine Biernacki and Karolina Wosik and Jack P. Antel},
  journal={Glia},
  year={2001},
  volume={36 2},
  pages={
          145-55
        }
}
The blood-brain barrier (BBB) is a specialized structure of the central nervous system (CNS) that restricts immune cell migration and soluble molecule diffusion from the systemic compartment into the CNS. Astrocytes and microglia are resident cells of the CNS that contribute to the formation of the BBB. In this article, we consider the influence of these glial cells on the immune regulatory functions of the microvascular endothelium, with special emphasis on the human BBB. A series of in vitro… CONTINUE READING
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