Glial Asthenia and Functional Paralysis: A New Perspective on Neurodegeneration and Alzheimer's Disease.

@article{Verkhratsky2015GlialAA,
  title={Glial Asthenia and Functional Paralysis: A New Perspective on Neurodegeneration and Alzheimer's Disease.},
  author={Alexei Verkhratsky and Amelia Marutle and Jos{\'e} J Rodr{\'i}guez-Arellano and A. Nordberg},
  journal={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
  year={2015},
  volume={21 5},
  pages={552-568}
}
Neuroglia are represented by several population of cells heterogeneous in structure and function that provide for the homeostasis of the brain and the spinal cord. Neuroglial cells are also central for neuroprotection and defence of the central nervous system against exo- and endogenous insults. At the early stages of neurodegenerative diseases including Alzheimer's disease neuroglial cells become asthenic and lose some of their homeostatic, neuroprotective, and defensive capabilities… CONTINUE READING