Glia cell stimulating factor (GSF): A new lymphokine: Part 2. Cellular sources and partial purification of human GSF
@article{Fontana1982GliaCS, title={Glia cell stimulating factor (GSF): A new lymphokine: Part 2. Cellular sources and partial purification of human GSF}, author={A. Fontana and U. Otz and A. L. Week and P. Grob}, journal={Journal of Neuroimmunology}, year={1982}, volume={2}, pages={73-81} }
Glia cell proliferation is characteristic of many inflammatory and degenerative processes in the brain, however the mechanisms underlying this response are poorly understood. We described a glia cell stimulating factor (GSF), produced by murine spleen cells, which activates DNA- and RNA synthesis of cultured glia cells. In the present series of experiments, we examined the ability of Concanavalin A (ConA)-stimulated human peripheral blood mononuclear leukocytes (PBM) and two continuous cell… CONTINUE READING
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