Glia cell stimulating factor (GSF): A new lymphokine: Part 2. Cellular sources and partial purification of human GSF

@article{Fontana1982GliaCS,
  title={Glia cell stimulating factor (GSF): A new lymphokine: Part 2. Cellular sources and partial purification of human GSF},
  author={A. Fontana and U. Otz and A. L. Week and P. Grob},
  journal={Journal of Neuroimmunology},
  year={1982},
  volume={2},
  pages={73-81}
}
  • A. Fontana, U. Otz, +1 author P. Grob
  • Published 1982
  • Biology, Medicine
  • Journal of Neuroimmunology
  • Glia cell proliferation is characteristic of many inflammatory and degenerative processes in the brain, however the mechanisms underlying this response are poorly understood. We described a glia cell stimulating factor (GSF), produced by murine spleen cells, which activates DNA- and RNA synthesis of cultured glia cells. In the present series of experiments, we examined the ability of Concanavalin A (ConA)-stimulated human peripheral blood mononuclear leukocytes (PBM) and two continuous cell… CONTINUE READING
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