Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Müller Cells and Retinal Ganglion Cells

  title={Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of M{\"u}ller Cells and Retinal Ganglion Cells},
  author={Dorte Marie Skytt and Anne Katrine Toft-Kehler and Charlotte Taul Br{\ae}ndstrup and S. Cejvanovic and Iswariyaraja Sridevi Gurubaran and Linda H Bergersen and Miriam Kolko},
  booktitle={BioMed research international},
Glia-neuron partnership is important for inner retinal homeostasis and any disturbances may result in retinal ganglion cell (RGC) death. Müller cells support RGCs with essential functions such as removing excess glutamate and providing energy sources. The aim was to explore the impact of Müller cells on RGC survival. To investigate the Müller cell/RGC interactions we developed a coculture model, in which primary Müller cells were grown in inserts on top of pure primary RGC cultures. The impact… CONTINUE READING


Publications citing this paper.


Publications referenced by this paper.
Showing 1-10 of 65 references

Neuroprotection by ratMüller glia against high glucose-induced neurodegeneration through amechanism involvingERK1/2 activation,”Experimental

  • A. Matteucci, L. Gaddini, M. Villa
  • Eye Research,
  • 2014
2 Excerpts

Similar Papers

Loading similar papers…