Glia Engulf Degenerating Axons during Developmental Axon Pruning

  title={Glia Engulf Degenerating Axons during Developmental Axon Pruning},
  author={Ryan J. Watts and Oren Schuldiner and John Perrino and Camilla H. Larsen and Liqun Luo},
  journal={Current Biology},
Developmental axon pruning is widely used in constructing the nervous system. Accordingly, diverse mechanisms are likely employed for various forms of axon pruning. In the Drosophila mushroom bodies (MB), gamma neurons initially extend axon branches into both the dorsal and medial MB axon lobes in larvae. Through a well-orchestrated set of developmental events during metamorphosis, axon branches to both lobes degenerate prior to the formation of adult connections. Here, we analyze… CONTINUE READING
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