Gli/Zic factors pattern the neural plate by defining domains of cell differentiation

@article{Brewster1998GliZicFP,
  title={Gli/Zic factors pattern the neural plate by defining domains of cell differentiation},
  author={R. C. Brewster and Juliet Lee and Ariel Ruiz i Altaba},
  journal={Nature},
  year={1998},
  volume={393},
  pages={579-583}
}
Three cell types differentiate in the early frog neural plate: neural crest at the lateral edges, floorplate at the midline and primary neurons in three bilateral stripes. Floorplate cells and ventral neurons are induced by Sonic hedgehog, (Shh) and neural crest and dorsal neurons are induced by epidermal factors such as bone morphogenetic proteins (BMPs). Neurogenesis in a subset of cells within the stripes involves lateral inhibition. However, the process by which pools of precursors are… CONTINUE READING
Highly Influential
This paper has highly influenced 22 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
107 Citations
39 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 107 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

The representation of visual salience in monkey parietal cortex

  • J. P. Gottlieb, M. Kusonoki, M. E. Goldberg
  • Nature
  • 1998

A role for Xenopus Gli - type zinc finger proteins in the early embryonic patterning of mesoderm and neuroectoderm

  • A. Ruiz i Altaba
  • Mech . Dev .
  • 1997

Catching a Glimpse of hedgehog

  • N. E. Baker, S.-Y. Yu
  • Cell
  • 1997

The expression of the mouse Zic 1 , Zic 2 and Zic 3 genes suggests an essential role for Zic genes in body pattern formation

  • J. Aruga
  • Dev . Biol .
  • 1997

Similar Papers

Loading similar papers…