Gleason 6 prostate cancer: serious malignancy or toothless lion?

  title={Gleason 6 prostate cancer: serious malignancy or toothless lion?},
  author={Herbert Lepor and Nicholas M. Donin},
  volume={28 1},
Autopsy studies of men without known prostate cancer suggest that a substantial reservoir of prostate cancer that does not cause symptoms or death exists within the population. The majority of these cancers are Gleason 6 tumors and are frequently detected by prostate-specific antigen-based prostate cancer screening.There is strong evidence from longitudinal cohort studies of men with both treated and untreated Gleason 6 prostate cancer to suggest that Gleason 6 disease, when not associated with… CONTINUE READING
Highly Cited
This paper has 21 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-9 of 9 extracted citations

Gleason 6 cancer is still cancer.

View 7 Excerpts
Highly Influenced

Diffuse reflectance spectroscopy can differentiate high grade and low grade prostatic carcinoma

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) • 2016
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 43 references

Active surveillance program for prostate cancer: an update of the Johns Hopkins experience.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2011
View 6 Excerpts
Highly Influenced

A molecular signature predictive of indolent prostate cancer.

Science translational medicine • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…