Glatiramer acetate treatment in PPMS: why males appear to respond favorably.

  title={Glatiramer acetate treatment in PPMS: why males appear to respond favorably.},
  author={Jerry S. Wolinsky and Tzippy Shochat and Sivan Weiss and David Ladkani},
  journal={Journal of the neurological sciences},
  volume={286 1-2},
In a large multicenter randomized, and double blind placebo controlled trial of glatiramer acetate (GA) in primary progressive multiple sclerosis (PPMS), an originally unplanned post hoc analysis suggested that males assigned to GA therapy experienced less progression of disability than their counterparts assigned to placebo; no similar potential treatment differences were seen among the females in this study. In this report we further explore the data from that trial in an attempt to determine… CONTINUE READING

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