Glatiramer acetate positively influences spinal motoneuron survival and synaptic plasticity after ventral root avulsion.


Avulsion of ventral roots induces degeneration of most axotomized motoneurons. At present there are no effective strategies to prevent such neuronal loss and to preserve the affected spinal circuits. Interestingly, changes in the spinal cord network also occur during the course of the experimental model of multiple sclerosis (experimental autoimmune… (More)
DOI: 10.1016/j.neulet.2008.12.017


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