The adrenergic system has an important role in normal central nervous system function as well as in brain disease. The locus coeruleus, the main source of norepinephrine in brain, is involved in the regulation of learning and memory, reinforcement of sleep-wake cycle and synaptic plasticity. In Alzheimer’s disease, locus coeruleus degeneration is observed… (More)


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@inproceedings{Femminella2016GiuseppeR, title={Giuseppe Rengo-CNS&ND-MS}, author={Grazia Daniela Femminella and Dario Leosco and Nicola Ferrara and Giuseppe Rengo}, year={2016} }